Types of PI

Primary Immunodeficiency (PI) is an umbrella term for over 300 genetic defects and disorders of the immune system recognized by the World Health Organization. Together they affect approximately 29,000 Canadians. Primary Immunodeficiency is not considered a rare disease as a category, but each individual form of PI is rare.

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There are 1 names in this directory beginning with the letter M.
MyD88 Deficiency
MyD88 (myeloid differentiation primary response protein 88) is a protein that allows the innate immune cell to function as normal. MyD88 deficiency is an inherited disorder where individuals suffer from recurrent and severe pyogenic (produces pus) bacterial infections. While individuals are susceptible to infections with S. pneumoniae, S. aureus, and P. aeruginosa, their immune systems could resist all other forms of bacteria, viruses, fungi, and parasites. It's been observed that the susceptibility to infection in general improved with age. The number of infections are reduced approximately around the age of 10. The estimated frequency of MyD88 Deficiency is unknown. Credits: Immune Deficiency Foundation, Genetics Home Reference
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