Primary Immunodeficiency (PI) is an umbrella term for over 350 genetic defects and disorders of the immune system recognized by the World Health Organization. Together they affect approximately 29,000 Canadians. Primary Immunodeficiency is not considered a rare disease as a category, but each individual form of PI is rare.
There is currently 1 name in this directory beginning with the letter B.
B-actin Deficiency
β-actin Deficiency coincides with poor granulocyte movement (chemotaxis) and recurring infections.
β-actin is a protein that allows cell movement. Some individuals that suffer from this condition, along with other chemotactic disorders, suffer from early tooth loss and severe gum infection (periodontitis).
Credits: Immune Deficiency Foundation, Genetics Home Reference